Paley Institute's Jason Weisstein, MD, MPH, FACS

Jason Weisstein

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It is with great pleasure that we announce that Dr. Jason S. Weisstein has joined the Paley Institute to lead our new Center for Joint Preservation and Replacement, and Center for Musculoskeletal Oncology. Dr. Weisstein’s practice focuses on both the conservative and surgical management of hip and knee conditions as well as musculoskeletal oncology. He performs hip and knee replacement using the latest techniques including direct anterior hip replacement and minimally invasive, patient customized knee surgery. From an oncology perspective, he is an expert at limb salvage, the surgical treatment of bone and soft tissue tumors, orthopedic conditions arising in cancer patients (i.e., avascular necrosis), and metastatic disease.

Dr. Weisstein, a native of southern California, graduated Valedictorian and a member of the Alpha Omega Alpha national medical honor society from the Mount Sinai School of Medicine in New York City in 1998. He subsequently completed his surgical internship and orthopedic surgery residency training at the University of California, San Francisco and then went on to receive fellowship training at the University of Washington.

Prior to his arrival at the Paley Institute, Dr. Weisstein directed one of the highest volume joint replacement programs in California at Eisenhower Medical Center where he specialized in state of the art direct anterior approach hip replacement and patient specific knee replacement. Dr. Weisstein was one of a few orthopedic surgeons in southern California recognized by his peers in 2015 for outstanding clinical care and was awarded a Castle Connolly Top Doctor Award.

Dr. Weisstein on Top Doctors 2015

Dr. Weisstein has also spent a significant part of his career in academics. He worked as an Assistant Professor of Orthopedic Surgery at the renowned University of Washington and Seattle Children’s Hospital, with a dual specialization in hip and knee reconstruction, as well as bone and soft tissue tumors. While in Washington, Dr. Weisstein trained orthopedic surgery residents and co-directed the musculoskeletal oncology fellowship. 

Dr. Weisstein was selected as a Fellow by both the American Association of Hip and Knee Surgeons and the American College of Surgeons, elite societies reserved for highly trained surgeons who adhere to the highest ethical and professional standards. Dr. Weisstein currently serves as an elected member of the Musculoskeletal Tumors and Diseases Committee of the American Academy of Orthopaedic Surgeons.

Dr. Weisstein on the Anterior Approach to Hip Replacement

Dr. Weisstein on Custom Fit Knee Replacement

Dr. Weisstein has presented original research at both the national and international level, published in major orthopedic textbooks and journals, and currently serves as a reviewer for several peer reviewed journals. Dr. Weisstein is actively involved in several orthopedic research and development projects and has served as a principal investigator for one of the United States’ first joint replacement registries. 

Dr. Weisstein is fluent in Spanish. He played collegiate baseball and continues to be an avid cross-fitter and obstacle course racer.

When Cancer Spreads to Bone

Cancer can spread into bones - developing into metastatic bone disease which can lead to pain, weakened bones, and fractures in some patients.

Dr. Weisstein developed these videos with UW Medicine to explore this topic.